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I've got a Ph.D. in quantum physics but now I'm a little in business so my background is going to waste. Sometimes my hands are itching to make some calculation, to solve some differential equations etc. :)
Here is some math:

To understand the formula please see the reference on mathematical notations

Pijl is an operator that characterize the possible actions (call, raise or fold for certain amount of money) of i-th player for in j-th time in l-th hand. This operator acts on the vector space phi of possible open cards on every k-th street. The operator P is a model of player that describes his all possible actions in different situation.
The column on the right side of the equation shows current and expected Wi winnings of the i-th Player.
I did not take into an account SB&BB singularity when person who were acting last preflop should act first postflop for the sake of easiness.
1) Every time Villain has to make a decision he should virtually "solve" a lot of differential equation (or multiply matrices) and find an optimal decision.
3) Hidden power of raise (even min-raise it doesn't matter) - you give your opponent the right to solve equation where can he easily can make a mistake and solve this problem non-optimally.
4) According to this formula I would reformulate Fundamental Theorem of Poker:
One should play his hands the way that maximizes his expected winnings.
Consequences:
1) According to the formula the sum in the beginning and Wexp in the end (here is metagame!) you can loose in one particular hand but if you expect to play more with this player and you think it will help you maximize your winning then go ahead.
3) The difference between high-stakes and nano-limits is the considerable difference of player pools hence there is a difference in probability to play certain amount of hands and expected winnings vs. certain Villain. Hence strategies for different P(number of hands) and Wexp (expecting winnings/looses) should be different.
Nano-limits: P is small, Wexp per hand is bigger.
High-Stakes: P is big, Wexp per hand is smaller.
3) Table Selection. You should not play with players where your expected Wexp is zero or negative.
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